Deadlines

15 March 2011

Application for EBSA bursaries

30 April 2011

Submission of abstracts

31 May 2011

Notification on acceptance of abstracts

30 June 2011

Early registration fee payment

30 June 2011

Cancellation without penalty

30 June 2011

Hotel reservation

23-27 August 2011

Date of the Congress

Recent updates

2011-09-06

Congress related videos have been published
EBSA 2011 Videos >>

2011-09-06

Picture gallery has been launched
EBSA 2011 Gallery >>

2011-08-18

Final Program booklet launched
Click here to read >>

2011-08-16

Scientific Programme updated
Check the latest version

2011-08-11

The online version of the Book of abstracts has been launched
Click here to read >>

2011-07-26

Terms of use of the EBSA2011 5-day public transportation pass is published
Read more >>

2011-07-26

Floor plan of the congress venue updated
View >>

2011-07-20

List of exhibitors
and Exhibition floor plan updated

Read more >>

2011-07-20

Final list of posters updated with poster locations
Read more >>

2011-07-20

Scientific Programme updated
Read more >>


Scientific programme

FINAL PROGRAMME BOOKLET (launched on 18 August)

Please click here to read the online version of the Book of Abstracts

Please click here to read the EBSA Prize winner article

Please click here to see confirmed plenary speakers


Overview timetable
Timetable


Scientific Programme

PDF version can be downloaded from here

The List of Posters can be downloaded from here

The location of posters can be seen on the floor plan of the venue


TUESDAY, AUGUST 23rd 2011
ELTE University Congress Center

14.00-19.00 Registration

17.00-17.30 Opening Ceremony
Globe Hall

17.30-18.30 OPENING LECTURE

Ada Yonath, Department of Structural Biology, Weizmann Institute, Rehovot, Israel (O-001)
View into the ribosomal exit tunnel
Globe Hall

Chair: Anthony Watts, Oxford, UK

18.30-19.45 Welcome Reception

 


WEDNESDAY, AUGUST 24th 2011
ELTE University Congress Center

9.00-10.00 EBSA PRIZE LECTURE

Kinneret Keren, Technion, Israel Institute of Technology, Haifa, Israel (O-002)
The interplay between actin dynamics and membrane tension determines the shape of moving cells
Globe Hall

Chair: Michael A. Ferenczi, London, UK

10.30-12.45 1. BIOMOLECULAR INTERACTIONS
Globe Hall
Chairs: Catherine Royer
, Péter Maróti

Invited speakers:
Sarah Cianferani
, Strasbourg, France (O-025)
Native mass spectrometry to decipher interactions between biomolecules

Jelle Hendrix, Leuven, Belgium (O-046)
Visualizing and quantifying HIV-host interactions with fluorescence microscopy

Short talks:
Stephan Grage,
Kahlsruhe, Germany (O-043)
Crowding of membrane proteins and peptides

Pietro Parisse, Trieste, Italy (O-073)
Enzymatic reactions in nanostructured surfaces: unzipping and cutting the double helix

Masahide Terazima, Kyoto, Japan (O-096)
Time-resolved detection of protein-protein interaction

Anna Wypijewska, Warsaw, Poland (O-107)
Experimental physics resources for studying biological macromolecules; deep insight into DcpS enzymatic hydrolysis of short capped mRNAs

László Smeller, Budapest, Hungary (O-090)
Unfolding of the cod parvalbumin Gad m1 allergen by high pressure

10.30-12.45 2. NEURONAL SYSTEMS AND OPTOGENETICS
Conference Hall
Chairs: Thomas Knöpfel
, Zoltán Nusser

Invited speakers:
Thomas Knöpfel
, Wako, Japan (O-111)
Optogenetic electrophysiology

Máté Lengyel, Cambridge, UK (O-118)
Neuronal biophysics: optimised for information processing?

Zoltán Nusser, Budapest, Hungary (O-120)
Subcellular compartment-specific distribution of voltage-gated ion channels

Short talks
Emily Ferenczi,
Stanford, USA (O-114)
Opsin stability under varying stimulation conditions

Martin Kopani, Bratislava, Slovakia (O-117)
Hematite particles in human brain

Joanna Mattis, Stanford, USA (O-119)
An analysis of new and existing opsins for scientific application

10.30-12.45 3. CALCIUM FLUXES, SPARKS & WAVES
János Bólyai Hall
Chairs: Ernst Niggli, László Csernoch

Invited speakers
Niall Macquaide
, Leuven, Belgium (O-126)
High sensitivity of Ca2+ wave propagation to ryanodine receptor inhibition in cardiac myocytes

Francesco Zorzato, Ferrara, Italy (O-131)
Calcium influx analysis by TIRF microscopy on myotubes from patients with RYR1 mutations linked to MH and CCD

Ernst Niggli, Bern, Switzerland (O-127)
Alterations of ryanodine receptor (RyR) function and arrhythmogenic Ca2+ waves in cardiomyocytes

László Csernoch, Debrecen, Hungary (O-130)
Caffeine and depolarization alters the morphology of calcium spark in amphibian skeletal muscle

Short talk
Dirk Gillespie,
Chicago, USA (O-125)
A simple model to describe single and multichannel calcium regulation of ryanodine receptors

12.45-15.00 POSTER SESSION & EXHIBITS (LUNCH BREAK)

15.00-16.00 PLENARY LECTURE

Holger Stark, Max-Planck-Institut für biophysikalische Chemie, Göttingen, Germany (O-003)
Structure determination of dynamic macromolecular complexes by single particle cryo-EM
Globe Hall

Chair: Erick J. Dufourc, Bordeaux, France

16.30-18.45 4. MEMBRANE LIPIDS, MICRODOMAINS & SIGNALLING
Globe Hall
Chairs:
Petra Schwille, János Matkó

Invited speakers
Didier Marguet,
Marseille, France (O-188)
Spot variable Fluorescence Correlation Spectroscopy reveals fast scouting of K-Ras at the plasma membrane of living cells

Christian Eggeling, Göttingen, Germany (O-142)
Imaging membrane heterogeneities and domains by super-resolution STED nanoscopy

Petra Schwille, Dresden, Germany (O-182)
Minimal systems for membrane associated cellular processes

Short talks
Nicolas Destainville,
Toulouse, France (O-139)
Role of long-range effective protein-protein forces in the formation and stability of membrane protein nano-domains

Erick Dufourc, Bordeaux, France (O-141)
Magnetic camemberts and liposomes: New tools for structural biology of membrane molecules

Nicky Ehrlich, Copenhagen, Denmark (O-143)
Ca2+ controlled all-or-none like recruitment of synaptotagmin-1 C2AB to membranes

16.30-18.45 5. AGGREGATED PROTEINS
Conference Hall
Chairs: Michele Vendruscolo
, Miklós Kellermayer

Invited speakers
Tuomas Knowles
, Cambridge, UK (O-200)
Kinetics of protein aggregation

Sara Linse, Lund, Sweden (O-205)
Mechanistic insights into Aß42 aggregation and effects of inhibitors

Short talks
Martino Calamai,
Florence, Italy (O-192)
Amyloid-like aggregates alter the membrane mobility of GM1 gangliosides

Sylvie Noinville, Paris, France (O-208)
Membrane permeabilization by purified soluble beta-enriched oligomers of prion protein

Anja Stefanovic, Twente, The Netherlands (O-213)
Mechanistic insights into oligomeric alpha-synuclein/membrane interactions

Annelies Vandersteen, Brussels, Belgium (O-218)
Biophysical consideration of gamma-secretase modulation as potential target for Alzheimer's disease

Bojan Zagrovic, Vienna, Austria (O-219)
Microscopic analysis of protein oxidative damage: effect of carbonylation on structure, dynamics and aggregability of villin headpiece

16.30-18.45 6. NUCLEIC ACID AND CHROMATIN STRUCTURE & FUNCTION
János Bólyai Hall
Chairs: Sanford H. Leuba
, Jörg Langowski

Invited speakers
Antoine van Oijen
, Groningen, The Netherlands (O-238)
Single-molecule studies of DNA replication

Jean-Marc Victor, Paris, France (O-239)
In silico single molecule manipulation with rigid body dynamics: an efficient tool for modeling the mechanical properties of DNA-protein complexes

Short talks
Vera Böhm, Heidelberg, Germany (O-225)
Nucleosome accessibility investigated using single molecule fluorescence

Péter Brazda,
Debrecen, Hungary (O-226)
Dissecting the role of coregulator exchange and chromatin binding in retinoic acid receptor (RAR) mobility by live cell FCS

Nikolay Korolev, Singapore, Republic of Singapore (O-230)
Chromatin condensation: general polyelectrolyte association and histone-tail specific folding

Carlo Manzo, Castelldefels (Barcelona), Spain (O-232)
Lambda genetic switch sensitivity depends on complex looping kinetics driven by nonspecific binding

Jeff Stear, Berlin, Germany (O-236)
DNA replication machinery clamps down on chromatin mobility

 


THURSDAY, AUGUST 25th 2011
ELTE University Congress Center

9.00-10.00 PLENARY LECTURE

Tamás Balla, Section on Molecular Signal Transduction, Program for Developmental Neuroscience, NICHD, National Institutes of Health, Bethesda, USA (O-004)
Detection and rapid manipulation of phosphoinositides with engineered molecular tools
Globe Hall

Chair: László Mátyus, Debrecen, Hungary

10.30-12.45 7. COMPUTATIONAL BIOPHYSICS AND SIMULATION
Globe Hall
Chairs: Helmut Grubmüller, István Simon

Invited speakers
Andrea Vaiana
, Göttingen, Germany (O-310)
Molecular dynamics simulations of ribosomal translocation based on Cryo-EM data

Nir Ben-Tal, Tel Aviv, Israel (O-247)
Using low-resolution structural data to model structure, function and motion in transmembrane proteins

Short talks
Lennart Nilsson,
Stockholm, Sweden (O-286)
Nucleotide modifications and tRNA anticodon- mRNA codon interactions on the ribosome

Stefano Piana-Agostinetti, New York, USA (O-293)
The quest for the perfect force field

Tatjana Skrbic, Trento, Italy (O-302)
The role of non-native interactions in knotted proteins

András Szilágyi, Budapest, Hungary (O-308)
Segment swapping between domains is an evolutionary mechanism that generates new protein folds

Ilpo Vattulainen, Tampere, Finland (O-313)
Trafficking of lipids between high density lipoprotein and cholesteryl ester transfer protein

10.30-12.45 8. IMAGING AND OPTICAL MICROSCOPY
Conference Hall
Chairs: Vinod Subramaniam, János Szöllősi

Invited speakers
Alberto Diaspro
, Genoa, Italy (O-329)
Optical nanoscopy and individual molecule localization with focused light under linear and non linear regimes

Werner Kühlbrandt, Frankfurt, Germany (O-341)
Cryo-EM of membranes and membrane proteins

Short talks
Donna J. Arndt-Jovin,
Göttingen, Germany (O-321)
Programmable Array Microscope imaging of living cells and spin-off to tumor diagnostics

Virginijus Barzda, Toronto, Canada (O-322)
Three-dimensional video-rate nonlinear microscopy of contracting myocytes

Benjamien Moeyaert, Leuven, Belgium (O-343)
Rational design and applications of photoconvertible and bi-photochromic fluorescent proteins

Vinod Subramaniam, Twente, The Netherlands (O-349)
Integrin-dependent activation of the JNK signaling pathway in live cells by mechanical stress

Thomas van Zanten, Barcelona, Spain (O-350)
Direct mapping of nanoscale compositional connectivity on intact cell membranes

10.30-12.45 9. MOLECULAR MOTORS
János Bólyai Hall
Chairs: M. A. Ferenczi, M. Nyitrai

Invited speakers
Toshio Yanagida
, Osaka, Japan (O-369)
Switch between large hand-over-hand and small inchworm-like steps in myosin VI

Anne Houdusse, Paris, France (O-360)
How myosin traps and how actin triggers the release of phosphate at the beginning of force generation

Short talks
Marco Capitanio
, Florence, Italy (O-354)
Myosin on an optical leash: Load dependence of the working stroke in a single myosin head

Ryohei Chiwata, Tokyo, Japan (O-356)
Rotation of F1-ATPase with a protrusion-less gamma rotor

Michael Kolbe, Göttingen, Germany (O-361)
Assembly and function of the type 3 secretion system needle from Salmonella typhimurium

Anna Roujeinikova, Victoria, Australia (O-366)
Mechanism of the force generation in the bacterial flagellar motor: a structural biology perspective

Andrej Vilfan, Ljubljana, Slovenia (O-368)
Longitudinal and rotational motion of microtubules driven by the kinesin-14 motor ncd

12.45-13.45 POSTER SESSION & EXHIBITS (LUNCH BREAK)

13.45-14.45 PLENARY LECTURE

Ferenc Mezei, Research Institute for Solid State Physics and Optics, Budapest, Hungary (O-305)
Spectroscopic explorations of the nature of protein dynamics
Globe Hall

Chair: J. Antoinette Killian, Utrecht, The Netherlands

14.45-17.00 10. STRUCTURE OF PROTEINS AND PROTEIN COMPLEXES
Globe Hall
Chairs: Jose Carrascosa, Péter Závodszky

Invited speakers
Malcolm Walkinshaw
, Edinburgh, UK (O-408)
Structural and biochemical studies show divergent allosteric mechanisms in glycoytic enzymes

Susan Lea, Oxford, UK (O-393)
Structural insights into the control of type three secretion

Short talks
Tuomo Glumoff
, Oulu, Finland (O-382)
Structure-function relationships in different MFE-2 proteins by various biophysical techniques

Tommi Kajander,
Helsinki, Finland (O-389)
The structure of factor H in complex with C3d explains regulation of immune complement alternative pathway

Anthony Wilkinson, York, UK (O-410)
Structure of an Intercellular Channel Formed during Sporulation in Bacillus subtilis

Johann Klare, Osnabrück, Germany (O-392)
Conformational changes during GTPase activity induced self-assembly of human guanylate binding protein 1 revealed by EPR spectroscopy

14.45-17.00 11. LIVE CELL IMAGING (Prof. Sándor Damjanovich Symposium)
Conference Hall
Chairs: Alberto Diaspro
, György Vereb

Invited speakers
Tom Jovin
, Göttingen, Germany (O-425)
FRET approaches to signal transduction: from QD biosensors to live-cell EGFR signaling

Ranieri Bizzarri, Pisa, Italy (O-416)
Engineering the excited state of fluorophores for high resolution imaging of bio- and soft-matter

Short talks
Ana Morales Garcia,
Sheffield, UK (O-430)
SFM study of bacterial cell walls

Marina Kuimova, London, UK (O-427)
Measuring intracellular viscosity: from molecular rotors to Photodynamic Therapy of cancer

Andrew Shevchuk, London, UK (O-434)
Multifunctional ion conductance microscopy for biophysical studies at nanoscale

Markus Staufenbiel, Osnabrück, Germany (O-437)
Triple-colour super-resolution imaging in living cells

Stephen Webb, Harwell, UK (O-438)
Simultaneous, multicolour single molecule imaging of the entire ErbB receptor family in live cells

14.45-17.00 12. TRENDS IN NEUTRON SCATTERING FOR BIOLOGY
János Bólyai Hall
Chairs: Thomas Hauss, László Rosta

Invited speakers
Hans Frauenfelder
, Los Alamos, USA (O-444)
Protein dynamics explored by Mössbauer effect and neutron scattering

Maikel Rheinstädter, Hamilton, Canada (O-449)
Nanobiology: Membranes and proteins in motion

Short talks
Ralf Biehl,
Jülich, Germany (O-440)
Function of Phosphoglycerate Kinase enabled by large domain movements

Alexandre Chenal, Paris, France (O-441)
Deciphering membrane insertion of the diphtheria toxin translocation domain

Christine Ebel, Grenoble, France (O-442)
Fluorinated surfactants (FSs) for studying membrane proteins (MPs)

Stéphane Longeville, Gif-sur-Yvette Cedex, France (O-447)
Influence of macromolecular crowding on protein stability

Andreas Stadler, Jülich, Germany (O-451)
Thermal fluctuations of hemoglobin from different species

17.00-23.00 SOCIAL DINNER


FRIDAY, AUGUST 26th 2011
ELTE University Congress Center

9.00-10.00 PLENARY LECTURE

Ernst Bamberg, Department of Biophysical Chemistry, Max-Planck -Institute of Biophysics, Frankfurt (O-006)
Microbial Rhodopsins: Light-gated ion channels and pumps as optogenetic tools in neuro- and cell biology
Globe Hall

Chair: Alberto Diaspro, Genoa, Italy

10.30-12.45 13. CYTOSKELETON AND CELL MIGRATION
Globe Hall
Chairs: Jürgen Bereiter-Hahn, Judit Ovádi

Invited speakers
Christoph Schmidt
, Göttingen, Germany (O-472)
Control of the fast, slow and reverse gear of the yeast mitotic kinesin-5 Cin8

Josef Alfons Käs, Leipzig, Germany (O-463)
Are biomechanical changes necessary for tumor progression?

Paul Janmey, Philadelphia, USA (O-459)
Driving cytoskeletal remodeling by extracellular matrix mechanics

Short talks
Beáta Bugyi,
Pécs, Hungary (O-481)
Tropomyosin isoform specific regulation of nucleation factors

Siddharth Deshpande, Basel, Switzerland (O-453)
Dynamics of Confined Actin Networks in Microchambers

Pierre Recouvreux, Amsterdam, The Netherlands (O-470)
Automated image analysis of microtubule dynamics and maintenance of fission yeast cells morphology

10.30-12.45 14. ION CHANNELS: STRUCTURE AND FUNCTION
Conference Hall
Chairs: Florian Lesage, György Panyi

Invited speakers
Bernard Attali,
Tel Aviv, Israel (O-483)
Targeting the promiscuous voltage sensor of voltage-gated cations channels by novel gating-modifiers

Declan Doyle, Dublin, Ireland (O-486)
Over-expression of human ion channels and transporters for structural studies

Short talks
Aura Jimenez
, Mexico City, Mexico (O-491)
Effect of cholesterol and cytoskeleton on KV10.1 membrane distribution

Péter Lukács, Vienna, Austria (O-495)
Differential modulation of inactivated states by hydrophilic and hydrophobic sodium channel blockers

Lubica Lacinova, Bratislava, Slovakia (O-494)
Gating currents of low-voltage-activated T-type calcium channels family

Tibor Szántó G., Debrecen, Hungary (O-502)
Molecular rearrangements during slow inactivation of the Shaker-IR potassium channel

Ligia Toro, Los Angeles, USA (O-506)
Molecular characterization of BKCa channel in cardiac mitochondria

10.30-12.45 15. PHOTOSYNTHESIS
János Bólyai Hall
Chairs: Rienk van Grondelle, Győző Garab

Invited speakers
Holger Dau
, Berlin, Germany (O-515)
Photosynthetic water oxidation: From biophysics to solar fuels

Rienk van Grondelle, Amsterdam, Netherlands (O-534)
Excitation energy transfer and non-photochemical quenching in photosynthesis

Péter Maróti, Szeged, Hungary (O-527)
Relaxation of bacteriochlorophyll fluorescence in intact cells of photosynthetic bacteria

Short talks
László Kálmán,
Montreal, Canada (O-523)
Effect of hydrophobic mismatch on the light-induced structural changes in bacterial reaction centers

Jidnyasa Joshi, Frankfurt am Main, Germany (P-522)
Characterization of the light harvesting antenna system in the diatom Phaeodactylum tricornutum

Gert Schansker, Szeged, Hungary (O-530)
Variable chlorophyll fluorescence: in part a yield change due to light-induced conformational change

12.45-14.45 POSTER SESSION & EXHIBITS (LUNCH BREAK)

13.00-14.15 EXECUTIVE COMMITTEE BURSARY RECEPTION

14.45-16.00 EBSA GENERAL ASSEMBLY

16.00-17.00 PLENARY LECTURE

Philippe Bastiaens, Max Planck Institute of Molecular Physiology, Department of Systemic Cell Biology, Dortmund, Germany (O-007)
The spatial organization of growth factor signaling systems in cells
Globe Hall

Chair: Manuel Prieto, Lisbon, Portugal

17.30-19.45 16. ELECTRON AND PROTON TRANSFER, BIOENERGETICS
Globe Hall
Chairs: Michael Verkhovsky, László Zimányi

Invited speakers
Janos K. Lanyi
, Irvine, USA (O-545)
Proton transfers in a light-driven proton pump

Jochen Blumberger, London, UK (O-537)
Computational Bioenergetics: From pure electron transfer in mono- and multi-heme cytochromes to chemistry in catalases

Short talks
Dimitri Khoshtariya,
Tbilisi, Georgia (O-544)
Mechanistic insights for redox-active proteins functionalized at Au/SAM junctions

Manuela Pereira, Lisbon, Portugal (O-548)
Sodium influence on energy transduction by bacterial complexes I

Andrei Pisliakov, Tokyo, Japan (O-549)
Mechanism of proton transfer in nitric oxide reductase: computational study

Ivo Saraiva, Oeiras, Portugal (O-552)
Molecular characterization of photosynthetic iron oxidation

László Zimányi, Szeged, Hungary (O-557)
Characterization of a vacuolar cytochrome b561 by redox titration and spectrum analysis

17.30-19.45 17. ION CHANNELS AND DISEASE
János Bólyai Hall
Chairs: Mustafa Djamgoz, Balázs Sarkadi

Invited speakers
Kenji Okuse
, London, UK (O-568)
Clustering of voltage-gated sodium channel Nav1.8 in lipid rafts is essential for action potential propagation in nociceptive unmyelinated axons

David Beech, Leeds, UK (O-562)
Calcium channels of vascular remodelling

Annarosa Arcangeli, Florence, Italy (O-558)
hERG1 channels: from antitargets to novel therapeutic targets in oncology.

Short talks
András Balajthy,
Debrecen, Hungary (O-559)
Analysis of the K+ current in human T cells in hypercholesterinaemic state

Karlheinz Hilber, Vienna, Austria (O-565)
Voltage-gated ion channel dysfunction precedes cardiomyopathy development ion the dystrophic heart

Ildikó Szabó, Padua, Italy (O-572)
Membrane-permeant inhibitors of the potassium channel Kv1.3 induce apoptosis in cancer cell lines

17.30-19.45 18. NEW AND NOTABLE
Conference Hall
Chairs: Anthony Watts,
Gábor Szabó

Invited speakers
Mark Howarth,
Oxford, UK (O-582)
Get a grip: engineering ultra-stable interactions to proteins for biophysics and medicine

Florian Lesage, Valbonne, France (O-580)
Background K+ channel gating and cell excitability

Pál Ormos, Szeged, Hungary (O-590)
Hydrodynamic synchronisation of light driven microscopic rotors

Andrew Turberfield, Oxford, UK
Protein structure by cryo-EM using DNA-templated protein arrays

Short talk
Károly Osvay,
Szeged, Hungary (O-589)
Towards attosecond biophysics: what can ELI-ALPS offer?

 


SATURDAY, AUGUST 27th 2011
ELTE University Congress Center

9.00-10.00 PLENARY LECTURE

Michael Grätzel, Laboratory of Photonics and Interfaces, Institute of Chemical Science and Engineering, Station 6, Ecole Polytechnique Fédérale, Lausanne, Switzerland, (O-008)
Molecular photovoltaics mimic photosynthesis
Globe Hall

Chair: Anthony J. Wilkinson, York, UK

10.30-12.45 19. MEMBRANE STRUCTURE
Globe Hall
Chairs: Manuel Prieto, Tibor Páli

Invited speakers:
Derek Marsh
, Göttingen, Germany (O-624)
Biophysics of membrane lipidomics

Gerhard Schütz, Linz, Austria (O-591)
Single molecule biology - Studying meetings within the plasma membrane

Timothy A. Cross, Tallahassee, USA (O-592)
The native M2 proton channel structure from Influenza A

Short talks
Gregor Anderluh,
Ljubljana, Slovenia (O-596)
Perforin induces invaginations in model membranes

Georg Pabst, Graz, Austria (O-631)
Stereo-specific effect of the analgesic drug ketamine on lipid membranes

Horia Petrache, Indianapolis, USA (O-632)
Dependence of gramicidin A channel lifetime on membrane structure obtained from x-ray scattering measurements

10.30-12.45 20. CONFORMATIONAL DYNAMICS, FOLDING AND IDP
Conference Hall
Chairs: Anthony Watts, Péter Tompa

Invited speakers:
Peter Wright
, La Jolla, USA (O-667)
Promiscuous liaisons: functional interactions of intrinsically disordered proteins in biological signaling

Mónika Fuxreiter, Budapest, Hungary (O-651)
Fuzziness in protein-DNA interactions: beyond what can be seen

Short talks
Mónika Bokor,
Budapest, Hungary (O-645)
Wide-line NMR and relaxation characterization of interfacial water in protein solutions

Karin Hauser, Konstanz, Germany (O-653)
Folding rates studied by a combination of static and time-resolved infrared spectroscopy

Julien Roche, Montpellier, France (O-659)
Probing cavities in SNase structure: a high pressure NMR study

Clemens Sill, Jülich, Germany (O-662)
Lactoferrin: Dynamics of a flexible protein in solution revealed by neutron scattering

Carine van Heijenoort, Gif-sur-Yvette, France (O-665)
How scarce sequence elements control the function of single ß-thymosin/WH2 domains in actin assembly

10.30-12.45 21. SYSTEMIC AND COLLECTIVE BEHAVIOURAL ASPECTS IN BIOLOGY
János Bólyai hall
Chairs: Carl Philipp Heisenberg, Tamás Vicsek

Invited speakers:
Ewa Paluch
, Dresden, Germany (O-676)
Polar actin cortex mechanics and cell shape stability during cytokinesis

Fernando Peruani, Dresden, Germany (O-677)
Transition to collective motion in bacterial colonies

Roberto Mayor, London, UK (O-673)
Collective migration of neural crest cells: a balance between repulsion and attraction

Short talks
Előd Méhes,
Budapest, Hungary (O-674)
Pattern formation by collective cell migration-driven segregation

Agnes Miermont, Paris, France (O-675)
Signaling cascade dynamics after a hyper-osmotic shock in the yeast Saccharomyces cerevisiae

András Czirók, Budapest, Hungary (O-668)
Vasculogenesis and collective movement of endothelial cells

12.45-14.00 POSTER SESSION & EXHIBITS (LUNCH BREAK)

14.00-16.15 22. SINGLE MOLECULE BIOPHYSICS
Globe Hall
Chairs: Christoph Schmidt, Imre Derényi

Invited speakers:
Ahmet Yildiz
, Berkeley, USA (O-714)
Cytoplasmic dynein moves through uncoordinated action of the AAA+ ring domains

Nynke Dekker, Delft, The Netherlands (O-686)
Single-molecule torque spectroscopy for biophysical investigations

Short talks
Pasquale Bianco,
Florence, Italy (O-680)
Millisecond-piconewton force steps reveal the kinetics of DNA overstretching

Nunilo Cremades, Cambridge, UK (O-685)
Direct observation of the interconversion of normal and pathogenic forms of alpha-synuclein

Rony Granek, Beersheba, Israel (O-688)
Protein dynamics and stability: Universality vs. specificity

Changjiang You, Osnabrück, Germany (O-715)
Self-controlled monofunctionalization of quantum dots and their applications in studying protein-protein interaction in live cells

Carolina Carrasco, Madrid, Spain (O-684)
Magnetic Tweezers studies of AddAB: a molecular motor for repairing broken DNA

14.00-16.15 23. MICRO AND NANOTECHNOLOGY
Conference Hall
Chairs: Klaus Fendler, András Dér

Invited speakers:
Klaus Fendler
, Frankfurt, Germany (O-727)
SSM-based electrophysiology: Transport mechanism and pH-regulation of the Na+/H+ antiporter NhaA from E. coli

Francesco Valle, Bologna, Italy (O-752)
Multiscale pattern fabrication for life-science applications

Joachim Heberle, Berlin, Germany (O-730)
Surface-Enhanced InfraRed Absorption Spectroscopy (SEIRAS) of membrane protein monolayers

Short talks
Péter Galajda,
Szeged, Hungary (O-728)
Swimming motility of bacteria near solid surfaces

Daniel Horak, Praha, Czech Republic (O-732)
Multifunctional magnetic nanoparticles for cell imaging

Kate Poole, Berlin, Germany (O-745)
Defining the forces required to gate mechanosensitive channels in mammalian sensory neurons

14.00-16.15 24. BIOENGINEERING &BIOTECHNOLOGY
János Bólyai Hall
Chairs: Gábor Forgács, Ferenc Vonderviszt

Invited speakers:
Gábor Forgács
, Columbia, USA (O-762)
Organ printing: the key to eternal life?

Loredana De Bartolo, Rende, Italy (O-758)
Membrane biohybrid systems for tissue and organ engineering

Short talks
Olivia Berthoumieu,
Oxford, UK (O-756)
Engineered bacteriorhodopsin: a molecular scale conductance photoswitch

Etienne Loiseau, Montpellier, France (O-769)
Continuous droplet interface crossing encapsulation for high through-put monodisperse vesicle design

Elisa Migliorini, Trieste, Italy (O-770)
Acceleration neuronal precursors differentiation induced by substrate nanotopography

Adél Muskotál, Veszprém, Hungary (O-771)
A polymerizable GFP variant

Anna Tugarova, Saratov, Russia (O-777)
FTIR spectroscopic study of biopolyester synthesis traits in the bacterium Azospirillum brasilense

16.45-17.45 CLOSING LECTURE

Akihiro Kusumi, Institute for Integrated Cell-Material Sciences (iCeMS), Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan (O-009)
Organizing principle of the plasma membrane: three-tiered meso-scale domain architecture revealed by single-molecule tracking
Globe Hall

Chair: Attila Jenei, Debrecen, Hungary

17.45-18.15 POSTER PRIZE AWARDS AND CLOSING CEREMONY

18.15-19.00 FAREWELL COCKTAIL

 


Confirmed plenary speakers

A. E. Yonath

Professor Ada Yonath (Weizmann Institute, Rehovot, Israel, and Max Planck Unit of Structural Molecular Biology, Hamburg, Germany)

Ada E. Yonath is the pioneer of ribosome crystallography. In 2009, she received the Nobel Prize in Chemistry along with Venkatraman Ramakrishnan and Thomas A. Steitz for her studies on the structure and function of the ribosome.
Ada E. Yonath was the first to observe that the ribosome is riddled with internal channels and chambers, including a cavern that hosts translation and a tunnel that protects newly synthesized proteins. These findings remained controversial for nearly a decade until they were confirmed by cryo-electron microscopy.

A. E. Yonath A. E. Yonath


Prof. Dr. Ernst Bamberg (Max Planck Institute of Biophysics, Department of Biophysical Chemistry, Frankfurt am Main)

His research is primarily directed towards the molecular mechanism of membrane transport proteins. One of the main topics is the electrophysiological and spectroscopic description of microbial rhodopsins. Dr. Bamberg is the coinventor of the light-gated cation channels channelrhodopsin1 and 2 (ChR1, ChR2). ChR2 is widely used as an optogenetic tool for optical manipulation of neural cells in culture as well as in living animals. This methodology has revolutionized the neuroscience with a perspective to biomedical applications.


Professor Tamás Balla (Section on Molecular Signal Transduction, Program for Developmental Neuroscience, NICHD, National Institutes of Health, Bethesda)

His research is primarily concerned with the roles of phosphoinositide lipids in cellular trafficking and signaling. His major interest is focused on the cellular functions of phosphatidylinositol 4-kinase enzymes but he also actively pursues methods by which to visualize and manipulate phosphoinositides in specific cellular compartments in intact living cells.



Professor Philippe Bastiaens (Department of Chemistry at the Technische Universität Dortmund, Max Planck Institute of Molecular Physiology)

His research interest has been directed towards understanding how the spatial organization of intracellular protein activities determines signaling dynamics and specificity. He developed quantitative experimental and theoretical approaches to derive and conceptualize physical principles that underlie the dynamics of signaling and cellular organization. He developed new approaches to the experimental elucidation of connections between reactions and the determination of enzyme kinetic parameters in living cells.


GrätzelProfessor Michael Grätzel (Ecole Polytechnique de Lausanne, Laboratory of Photonics and Interfaces)

He pioneered research on energy and electron transfer reactions in mesoscopic-materials and their application in solar energy conversion systems, optoelectronic devices and lithium ion batteries. He discovered a new type of solar cell based on dye sensitized nanocrystalline semiconductor oxide particles. His work has obtained 60'000 citations so far (h-index 114), ranking him amongst the 10 most highly cited chemists worldwide. He was selected by the Scientific American as one of the 50 top researchers in the world.


KusumiProfessor Akihiro Kusumi (The Research Centre for Nano Medical Engineering, The Institute for Frontier Medical Sciences, Kyoto University)

Professor Kusumi is a pioneer in membrane research. He developed fluorescence lifetime imaging (FLIM) techniques and methods for single-molecule observation and manipulation that can be applied to studying the plasma membrane in living cells. He discovered that the plasma membrane is partitioned into 30-200 nm compartments, in addition to the pulse-like activation of signalling molecules and introduced the Membrane "Skeleton Fence (Corral)" and the Anchored-Protein "Picket" Model.


MezeiProfessor Ferenc Mezei (Research Institute for Solid State Physics and Optics, Budapest)

Professor Mezei has been the Director of the Berlin Neutron Scattering Center. He is the originator of the ESS design concept, the long pulse spallation source. With long neutron pulses, more neutrons can be generated, thus providing significantly better quality scientific results and more scientific applications. He is also the inventor of the neutron spin-echo spectroscopy method, which has had far-reaching implications for the understanding of polymers, proteins, glasses and magnetic materials.


Holger StarkProfessor Holger Stark (Max-Planck-Institut für biophysikalische Chemie, Göttingen)

Professor Stark determined the 3D structure of large macromolecular complexes such as ribosomes and spliceosomes by single particle cryo-EM. His focus is on structural studies in a time and temperature dependent manner to better understand the function of large macromolecular complexes by simultaneous high-resolution structure determination and analysis of conformational dynamics. Recently, he has visualized tRNA movement and conformational dynamics of the ribosome and obtained a molecular movie of how tRNAs move through the ribosome.